![]() ![]() ![]() Low BUN-to-creatinine ratios may be linked with a diet low in protein, a severe muscle injury called rhabdomyolysis, pregnancy, cirrhosis, or syndrome of inappropriate antidiuretic hormone secretion (SIADH).Other conditions, such as heart failure and dehydration, can also cause low clearance levels. Kidney damage can be from conditions such as a life-threatening infection, shock, cancer, low blood flow to the kidneys, or urinary tract blockage. Low creatinine clearance levels can mean you have chronic kidney disease or serious kidney damage. ![]() Low levels can also mean some types of severe liver disease or a diet very low in protein. Low blood creatinine levels can mean lower muscle mass caused by a disease, such as muscular dystrophy, or by aging.A very high BUN-to-creatinine ratio may be caused by bleeding in the digestive tract. This may be caused by shock or severe dehydration. High BUN-to-creatinine ratios occur with sudden (acute) kidney problems.High creatinine clearance levels can be caused by carbon monoxide poisoning and pregnancy.This is low blood pressure with many causes including severe bleeding and very severe infection. These include crush injuries, burns, rhabdomyolysis, muscular dystrophy, polymyositis, and strenuous exercises. Kidney damage can be caused by a life-threatening infection, shock, cancer, or low blood flow to the kidneys. Serious kidney damage or chronic kidney disease.High creatinine blood levels can be caused by:.A value that isn't in the normal range may still be normal for you.īlood creatinine, creatinine clearance, and BUN-to-creatinine ratios can be measured. Your doctor will also look at your results based on your age, health, and other factors. Your lab report should show the range that your lab uses for each test. NormalĮach lab has a different range for what's normal. This value is the amount of blood cleared of creatinine per minute, based on your body size. The creatinine clearance value is found from the amounts of creatinine in the urine and blood and from the amount of urine you pass in 24 hours. These tests give information about how well your kidneys are working. Empty your bladder for the last time at or just before the end of the collection period.Īdd this urine to the large container.Keep the collected urine in the refrigerator for the collection time.Don't get toilet paper, pubic hair, stool (feces), menstrual blood, or anything else in the urine sample.Don't touch the inside of either container with your fingers. Then pour the urine into the large container. For the set period of time, collect all your urine.Įach time you urinate during this time period, collect your urine in a small, clean container.When you first get up, you empty your bladder.īut don't save this urine.You will use the container to collect your urine. Your doctor will give you a large container that holds about 1 gallon. You collect your urine for a period of time, such as over 4 or 24 hours. This ratio can help your doctor check for problems, such as dehydration, that may cause abnormal BUN and creatinine levels.Ī health professional uses a needle to take a blood sample, usually from the arm. The levels of blood creatinine and blood urea nitrogen (BUN) can be used to find the BUN-to-creatinine ratio. Urea is made in the liver and passed out of your body in the urine. Urea is a waste product made when protein is broken down in your body. This test measures the amount of urea in your blood. The test is done on both a blood sample and on a sample of urine collected over 24 hours. This test gives better information than a blood creatinine test on how well your kidneys are working. Creatinine clearanceĪ creatinine clearance test measures how well creatinine is removed from your blood by your kidneys. Men generally have higher creatinine levels than women. The amount of creatinine in the blood depends partly on the amount of muscle tissue you have. A high level may mean that your kidneys aren't working as they should. The blood creatinine level shows how well your kidneys are working. If your kidneys are damaged and can't work as they should, the amount of creatinine in your urine goes down while its level in your blood goes up. Your kidneys take creatinine out of your blood and pass it out of your body in urine. These tests tell how well your kidneys are working.Īnother substance, creatine (say "KREE-uh-teen"), is formed when food is changed into energy through a process called metabolism. Creatinine and creatinine clearance tests measure the level of the waste product creatinine (say "kree-AT-uh-neen") in your blood and urine. ![]()
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